Oncoscience covers the rapidly growing field of cancer research, especially emergent topics not currently covered by other journals. Cancer research has entered a new phase in which the convergence of information from different disciplines (e.g., cancer biology, bioinformatics, chemistry, and drug design among others) is beginning to provide new insight into tumor development and cancer treatment.

To capture the key elements of this phase, Oncoscience covers all aspects of the structure and function of oncogenes, growth suppressor and apoptotic genes, as well as their role in signal transduction and the mechanisms by which their expression and function are altered during tumor development. In addition to publishing manuscripts that directly relate to these areas of research, the journal covers the niche of interdisciplinary articles that bring together cancer biology, chemistry, and drug design.

Oncoscience also regularly publishes Editorials on emergent topics and commentaries on highly visible papers published in other journals.

Its international Editorial Board includes 65 members from different countries, including the USA (predominantly), United Kingdom, Sweden, France, Denmark and Spain. All are highly cited authors, professors at leading universities, and are supported by numerous NIH grants. The Editorial Board includes 20 members of the National Academy of Sciences (USA), 6 Lasker Award recipients (Brian Druker, Andrew Schally, Alexander Varshavsky, Stephen J. Elledge, William G. Kaelin,Jr., and Greg L. Semenza) and a Nobel Prize winner (Andrew Schally).